"Dr. Tremayne is an enigmatic psychiatrist running an asylum that houses four very special cases. Visited by his colleague Nicholas, Tremayne explains his amazing and controversial theories as to why each of the four patients went mad."
Jack Hawkins
as Dr. Nicholas
Donald Pleasence
as Prof. R.C. Tremayne
Georgia Brown
as Fay Patterson (segment "Mr. Tiger")
Donald Houston
as Sam Patterson (segment "Mr. Tiger")
Russell Lewis
as Paul (segment "Mr. Tiger")
David Wood
as Tutor (segment "Mr. Tiger")
Suzy Kendall
as Ann / Beatrice (segment "Penny Farthing")
Peter McEnery
as Timothy Patrick (segment "Penny Farthing")
Neil Kennedy
as 1st Removal Men (segment "Penny Farthing")
Richard Connaught
as 2nd Removal Man (segment "Penny Farthing")
Beth Morris
as Polly (segment "Penny Farthing")
Frank Forsyth
as Uncle Albert (segment "Penny Farthing")
Joan Collins
as Bella Thompson (segment "Mel")
Michael Jayston
as Brian (segment "Mel")
Kim Novak
as Auriol (segment "Luau")
Michael Petrovitch
as Kimo (segment "Luau")
Mary Tamm
as Ginny (segment "Luau")
Lesley Nunnerley
as Vera (segment "Luau")
Leon Lissek
as Keoki (segment "Luau")
Zohra Sehgal
as Malia (segment "Luau")
Charles Gray
as Nicholas (Clinic Link Episodes segment) (voice)
Freddie Francis
Director
Jennifer Jayne
Writer
Bernard Ebbinghouse
Original Music Composer
Ken Ritchie
Sound Recordist
Norman Priggen
Producer
Norman Warwick
Director of Photography
Bernard Gribble
Editor
Roy Walker
Art Direction
Eric Allwright
Makeup Artist
Nolan Roberts